The skull is a group of hard bones, which plays a great role in human health. It builds a strong fortress for the brain so that the intracranial tissues can operate and work normally. If the skull is damaged, the intracranial environment and intracranial pressure will become very unstable, which will cause a series of cranial defect syndrome and seriously affect the life and health of patients. Cranial defects should be taken seriously, and if the defect area is larger than 3cm, it is necessary to go to the hospital for cranial repair surgery in time. In neurosurgery, skull repair surgery is a very classic surgery, which has thousands of years of history and mature technology, so many hospitals can do it, but the focus is on the recovery and effect after surgery. The most important factor that really affects the outcome of the surgery is the repair material and the operation technique. Currently, most local hospitals use titanium mesh material, which is a metal material and not expensive, but post-operative problems occur, so you should choose a safer and more advanced material for skull repair surgery. The PEEK material that we currently use here is more ideal. It is an advanced polymer material, and its properties are particularly close to those of autologous cranial bone. Of course, in addition to the material, the physician’s experience and technique are also very important, especially since the repair of this new PEEK material is still different from the traditional operation, and requires us to continuously improve and upgrade the technology, and if necessary, integrate the concept of cosmetic surgery to make the post-operative results more natural-looking.