Lupus erythematosus generally refers to systemic lupus erythematosus (SLE), which is hereditary. SLE is an autoimmune disease, the cause of which is still unclear, but current research shows that SLE has a clear genetic predisposition, with a higher risk of developing the disease in people with a family history of the disease than in the general population, and is more prevalent in women of childbearing age. Common symptoms of SLE include skin rash, joint pain, fever, photosensitivity, etc. It may be complicated by lupus encephalopathy, interstitial lung lesions, pericarditis, lupus nephropathy, etc. Doctors need to diagnose the disease by combining the patient’s typical symptoms with the results of tests such as antinuclear antibody, and need to treat the disease with drugs such as prednisone, cyclophosphamide, cyclosporine, etc. The cause of SLE is not clear yet, but current studies show that the disease has a clear genetic predisposition in the family. SLE has a certain genetic predisposition, so patients with a family history of SLE need to closely monitor their symptoms and are advised to consult a doctor in a timely manner and follow the doctor’s instructions.