Zhu Sha An Shen Pill has the effects of clearing the heart and nourishing blood, calming the mind (using drugs of heavy sedative nature to stabilize the mind), and is used in treating irritable heat in the chest (irritable and sultry), palpitations (rapid heartbeat, often accompanied by panic), restlessness, and insomnia and excessive dreams. Zhu Sha An Shen Wan (朱砂安神丸) is composed of Zhu Sha (朱砂), Huang Lian (黄连), Di Huang (地黄), Angelica sinensis (当归), and licorice. It is mostly used for the treatment of insomnia and excessive dreaming, palpitation and palpitations (rapid heartbeat and panic), and restlessness caused by hyperactivity of heart fire and deficiency of yin and blood. Clinically, insomnia, palpitation, red tongue, and fine pulse (narrowing and thinning of pulse and accelerated rate) are the main points of diagnosis. This formula in the heavy town medicine (Zhu Sha) and bitter cold medicine (Huang Lian, Sheng Di) dosage is large, often served easy to damage the function of the spleen and stomach, so can not be taken for a long time; heart qi insufficiency, disturbed heart and spirit should not be used; avoid spicy and oily and stimulating food, tobacco and alcohol; due to indigestion, gastric and epigastric cacophony (the stomach has a feeling similar to hunger, emptiness with burning), and anxiety, insomnia and other contraindications; avoid taking pregnant women. Need to be under the guidance of a doctor to identify the evidence after the use of medication.