Closure is the injection of a certain concentration of hormone and numbing agent into the lesion area or the painful area, clinically commonly used Depo-Provera or prednisolone injection, numbing agent is usually applied to procaine hydrochloride or lidocaine, choose one of the mixture, and then injected into the painful point, also can be injected into the joint capsule or nerve trunk area. It provides a quick pain relief, reduces inflammation, and relieves muscle spasm. This treatment allows the drug to be injected directly into the lesion to maximize its therapeutic effect. From the point of view of the mechanism of action, the treatment of some tennis elbow, neck and shoulder pain, and low back pain is symptomatic treatment. But in medicine sometimes can also play the role of the root cause, before people will be closed treatment to do as a cure for the symptoms, in fact, this view is also incorrect, because sometimes the use of 1-2 times the closed treatment after some symptoms are completely disappeared or no longer recurring. Therefore, closure can sometimes cure some diseases.