There is no so-called best treatment for bone marrow edema of knee joint. Common causes of knee joint include trauma, knee joint inflammation, bone tumor, etc. According to the cause of the disease, you can choose physical therapy, medication and surgical treatment to treat it. 1. Trauma: Bone marrow edema caused by trauma and exertion is mainly treated with rest, avoiding weight-bearing activities, and active trauma treatment, such as hot compresses, infrared and other physical therapy, to promote inflammatory absorption, and most of the bone marrow edema will recover and heal on its own after the injury subsides. 2. Knee joint inflammation: such as degenerative disease, rheumatoid arthritis, septic infection, etc., resulting in inflammatory substances for bone marrow stimulation caused by bone marrow edema, should actively treat the primary disease, take ibuprofen or acetaminophen and other drugs to relieve pain, and if necessary, carry out closed treatment. 3. Bone tumor: bone tumor can cause bone marrow edema, it should be determined whether the tumor is benign or malignant, if it is benign tumor, surgical scraping, bone marrow edema can subside after tumor removal, if it is malignant tumor causing bone marrow edema, it should be treated by surgical treatment, chemotherapy and other methods. There are other causes of bone marrow edema of knee joint, such as osteoporosis, etc. It is suggested that patients should go to the hospital in time to have a detailed examination to judge the condition, and then choose the appropriate treatment method.