Long years of insomnia can lead to many kinds of diseases, and sleep is an important physiological function. Problems with physiological structure or physiological function will definitely bring pathological results, so poor sleep will bring about various system diseases: 1. A common hazard is tumor, the high incidence of tumor is related to poor sleep, many kinds of tumor necrosis factor and interleukins are produced in sleep for big changes and regulation. Poor sleep will lead to disorders in the immune system, low immunity, easy to catch a cold, easy to get infected, easy to develop special tumors; 2. The cognitive function of the patient will decline. After reading a book during the day, the brain will consolidate at night, consolidation is not to stay awake during the day to read 20 times, which is useless, because the fast eye movement period and non-fast eye movement period are very effective for memory consolidation, and effective for nerve repair. Now scientific research has found that the occurrence of dementia and sleep disorders are very close, so poor sleep may lead to cognitive decline and symptoms of dementia, which is very harmful; 3, endocrine system, blood sugar and lipid metabolism disorders are also inseparable from sleep. In sleep usually adrenaline, adrenal axis, etc. will be changed, these rhythm disorders will lead to the emergence of endocrine diseases, such as diabetes, obesity, while cardiac nerve regulation and sleep rhythm has a great relationship. So poor sleep can also cause malignant arrhythmias or can aggravate arrhythmias, or can increase the burden on the heart at night, leading to a high incidence of cardiovascular events at night.