Mouth sores on the tongue can be treated with topical medications, systemic medications, and dietary adjustments to promote the disappearance of mouth sores. 1. Local medication: you can apply ice boron powder or watermelon cream spray on the mouth sores, and at the same time with chlorhexidine gargle or compound boric acid solution gargle. If the mouth sores are large in size, you can choose submucosal closure, recombinant human epidermal growth factor gel for external use. 2. Systemic treatment: oral transfer factor or thymidine, etc., to enhance the body’s resistance, but also to promote the healing of mouth sores. 3. Dietary adjustments: recently to do a light diet, do not eat spicy stimulating food, avoid tobacco and alcohol stimulation, avoid staying up all night, can also promote the healing of mouth sores. Mouth sores on the tongue should not be blindly self-medication, timely to the hospital, under the advice of the doctor to choose the best treatment program, in order to facilitate the recovery of the condition.