The joint use of lumbar pain capsules should be avoided with acetaminophen, the preparation of the herb of the interaction of drugs, such as barbiturates or other antispasmodic drugs, aspirin, hemicrania and so on. Lumbar and knee pain capsule is often used in the treatment of rheumatoid arthritis, lumbar muscle strain, sciatica, etc., has the effect of activating blood circulation and removing blood stasis (to promote blood circulation and eliminate blood stasis in the body), relaxing tendons and activating collaterals (stretching the tendons and bones and dredging the meridians and collaterals), eliminating wind and relieving pain (dispersing the wind and relieving the pain of the tendons and bones), the formula contains the preparation of the grass wu, sole live, He Shouwu, Sang Sang Sheng, etc., and it also contains acetaminophen. Clinical co-medication should be noted that if large doses of acetaminophen and barbiturates or other antispasmodic drugs, may increase the risk of hepatotoxicity; with aspirin and other non-steroidal anti-inflammatory drugs, may increase the risk of nephrotoxicity; with anticoagulants, may increase the role of anticoagulants, need to adjust the dosage of anticoagulant drugs in a timely manner; and with Zidovudine, Chloramphenicol, may enhance the toxicity of the joint use. In addition, CaoWu contains aconitine, according to the principle of “eighteen against” in traditional Chinese medicine, it should be avoided to be used in combination with HanXia, GuaPuShu, BeiMu, smallpox pollen, BaiHe, BaiYiYan. After taking this product, some patients may experience adverse reactions such as nausea and vomiting, dizziness, palpitation (rapid heartbeat, often accompanied by panic), chest tightness, etc., which can be recovered after stopping the drug, and is prohibited for those who are allergic to the ingredients contained in this product. It is recommended that patients should standardize the application under the guidance of Chinese medicine practitioners, and should not blindly self-medicate.