High uric acid may cause numbness throughout the body, but the body numbness this symptom may also be the environment, drugs and other disease factors. 1. High uric acid: patients with uric acid salt in the limbs, bones, joints and peripheral nerves, blood vessels and other soft tissues to deposit, adhesion, may lead to numbness or joint pain, swelling and other symptoms. 2. Environment: When the temperature is low, the patient’s body may suffer from frostbite, which may also lead to numbness. In addition, if the patient is often exposed to neurotoxic substances such as lead and mercury due to work, it may also lead to numbness. 3. Drugs: chemotherapeutic drugs, some antiviral drugs, some anti-epileptic drugs, some cardiovascular drugs and some antibiotics may lead to peripheral neuropathy and lead to generalized numbness. 4. Other diseases: diabetes mellitus, lumbar disc herniation, cervical spondylosis, tuberculosis, malignant tumors, alcoholism and other diseases can also lead to generalized numbness symptoms. There may be other causes of generalized numbness, and it is recommended that patients with generalized numbness symptoms go to endocrinology, rheumatology and immunology departments of regular hospitals for detailed consultation and further diagnosis.