There are many accidents in life that often happen without notice. According to the survey, many people suffer from cranial defects due to an accident or a natural or man-made disaster, thus dealing a heavy blow to their health. Cranial defect is a major issue, if not repaired as soon as possible, it will not only have a great impact on the external appearance of the person, but also the brain tissue will easily suffer from secondary injury due to the loss of the normal cranial barrier protection, and it may also cause other complications. Therefore, when we have a skull defect problem, we have to restore our skull to integrity through cranial bone repair surgery. But how to calculate the size of skull defect? When is the right time for skull repair? This has become a concern for many patients in the repair process. It is understood that for the indications and timing of cranial repair, the neurosurgical guidelines stipulate that when the defect area is larger than 3 cm and there is no contraindication, the patient can be repaired 2-3 months after debridement. Some patients can also be repaired according to their actual situation, but of course the choice of repair material is very important. Our team is currently carrying out peek cranioplasty, which has achieved excellent results in the clinic. Polyetheretherketone PEEK, a polymer material, is gradually becoming a new trend in cranial repair materials due to its good biocompatibility, ability to be complexly shaped, excellent mechanical properties, good protective properties, and high postoperative comfort. It is also recommended that patients with cranial defects, cranial defects must go to a regular hospital for cranial repair to avoid delay and complications from other diseases.