Parotid lymphoma is a non-Hodgkin’s lymphoma that occurs in the parotid gland. After having parotid lymphoma, the first step is to improve various examinations. Superficial lymph node ultrasound, chest CT, abdominal ultrasound, bone marrow aspiration and PET-CT should be improved for clinical staging. For patients with stage I and II, radiotherapy can be considered first, and the remaining residual lesions can then be treated with chemotherapy. For patients with stage III and IV or higher, chemotherapy should be considered first, and the commonly used chemotherapy regimen is the CHOP regimen. If CD20 is positive, rituximab (i.e., melphalan) chemotherapy can also be added. The commonly used regimen is the R-CHOP regimen, and chemotherapy drugs include cyclophosphamide, vincristine, anthracycline chemotherapy drugs, and glucocorticoids, among others. After 6-8 courses of chemotherapy, radiation therapy can be given to the residual lesions to further kill the lymphoma tissue. In addition, for types with poor prognosis, autologous hematopoietic stem cell transplantation can be added to the treatment.