Children with hepatitis B should be treated with general treatment and medication according to their condition. 1. General treatment: children infected with hepatitis B can form immune tolerance state, mostly asymptomatic and become hidden infection and asymptomatic carriers, often without antiviral treatment, regular follow-up can be. Avoid daily labor, drinking and taking drugs that damage the liver. 2. Drug treatment: mainly applicable to children with chronic hepatitis B and abnormal liver function. (1) Drugs for improving and restoring liver function: commonly used are non-specific hepatoprotective drugs such as reduced glutathione and glucuronolactone, and anti-yellowing drugs such as potassium magnesium menthonate. (2) Immunomodulation: including thymic peptide, thymosin, transfer factor and so on. (3) Antiviral therapy: antiviral therapy can be applied if the viral load reaches a certain level or liver function is impaired. Commonly used drugs include interferon alpha, entecavir and so on. It is recommended to consult a doctor in time and choose a suitable treatment plan under the doctor’s guidance. The use of specific drugs should be under the guidance of a doctor.