Craniocerebral injury is a common disorder in neurosurgery, and is also a common trauma. Craniocerebral injury, according to the anatomical part of the skull can be generally divided into scalp injury, skull injury and brain injury, the three can be combined; and according to the degree of injury can be divided into light craniocerebral injury, medium craniocerebral injury, heavy craniocerebral injury and extra heavy craniocerebral injury. The common causes of craniocerebral injury are traffic accidents, falls from height, falls, industrial accidents and firearm injuries. For patients with severe craniocerebral injury, sometimes craniotomy may be required, and if intracranial hypertension is present, debridement and decompression will be required, leaving a skull defect after surgery. Some patients ask how to take care of the cranial defects left after decompression of the flap in heavy cranial injury like this, and how to take care of the unrepaired cranial bone. First of all, we should avoid strenuous exercise, pay attention to protection and avoid bumping; in addition, we should pay attention to keep the defect area dry and clean; we should pay attention to diet, both to ensure sufficient nutrition and to avoid too greasy meat and fishy, and keep a light and healthy diet; we should pay attention to rest, ensure sufficient sleep and avoid strain; in addition, we should keep a happy mood. The last and the most important point is still to carry out skull repair in time, generally about three months in the trauma surgery is the best time to repair. To do skull repair surgery, patients need to pay attention to two points, one is to choose the right repair material, but choose a good hospital doctor. Although cranial bone repair is a routine surgery, it is not simple, and the repair material is important, as are the surgical skills and perioperative care of the health care team. Currently, polyether ether ketone PEEK is an ideal material with excellent performance, and its properties are comparable to those of autologous cranial bone, which makes it highly protective, comfortable, and aesthetically pleasing when placed in the body, making it a new trend in cranial repair materials. Currently, our team is using PEEK as a cranial repair material, and we are constantly improving and upgrading our technology and optimizing the design of the material. We have also innovatively introduced the concept of aesthetic plastic surgery, so that we can carry out comprehensive PEEK cranial repair and plastic surgery, which can achieve anatomical integrity, functional perfection, and aesthetic appearance of the overall unity, and achieve good repair results, which are widely praised and appreciated.