Oral administration of ezetimibe does not usually lead to the occurrence of gallstones. Ezetimibe is a lipid-lowering drug, mainly for the treatment of primary hypercholesterolemia, familial hypercholesterolemia, etc. When taking this kind of drug orally in the clinic, it is noted that it should not be taken by the patients who are allergic to this product, patients with unexplained persistent increase in aminotransferase levels, patients with moderate or severe hepatic insufficiency, and children under the age of 10. Side effects of oral Ezetimibe are more frequent and may cause headache, abdominal pain, diarrhea, increased transaminase levels, angioneurotic edema, or even induce inflammation of the pancreas. Oral ezetimibe does not usually lead to the development of gallbladder stones. For specific questions about oral ezetimibe, consult a licensed pharmacist at your regular hospital.