There is no definite way to prevent melanoma. However, melanoma can be detected at an early stage. Generally speaking, melanoma can appear in any part of the body, but in China, more than 80% of melanoma occurs on the soles of the feet, fingers and toes, palms of the hands and even under the nails around the nails. Is melanoma an incurable disease? In fact, as long as malignant melanoma is detected early, the five-year survival rate is over 80%. The difficulty of treatment depends on whether the tumor is metastatic, the growth pattern and the depth of invasion. For early detection of malignant melanoma, the correct approach is to first remove the entire mole and send it all for pathological examination. It is important to note that the lesion must be uprooted, and the whole lesion together with the surrounding 0.5-1.0 cm of normal skin and subcutaneous fat should be removed. This is because malignant melanoma is highly malignant and easy to metastasize, and any stimulation such as squeezing can promote tumor dissemination. In addition, the doctor has to pay attention to whether there are residual nevus cells at the cut edge when removing the nevus, if the removal is not enough, further treatment is needed, otherwise the residual nevus cells are also very easy to become malignant. If the pathological test confirms that it is a malignant melanoma, then the surgery should be expanded to remove the skin and even the muscle near the malignant melanoma again to prevent it from spreading, and then combined with immunotherapy. Irregular moles are more likely to become malignant Generally speaking, the possibility of an atypical mole developing into a malignant melanoma is high. Atypical moles have the following five main characteristics: First, they are asymmetrical: ordinary moles are often round or oval, divided into two and symmetrical in both halves, while malignant melanoma is often irregular in shape; Second, the edges are irregular: ordinary moles have regular smooth and complete edges and are clearly demarcated from the surrounding skin, while the edges of malignant melanoma are often jagged and jagged; Third, the color is uneven and multiple shades exist at the same time: ordinary The common nevus is often brown, brown or black, while malignant melanoma often has various colors such as pink, white and blue-black on top of brown or tan, with uneven tones; fourth, larger diameter: common nevus is usually less than 6 mm, while malignant melanoma often exceeds 6 mm; fifth, multiple changes occur: including any possible changes, such as shape, size, surface enlargement, as well as bleeding, crusting, itching, etc.