Melanoma is a type of tumor that is found on the surface of the skin. In daily life, many people are ignorant about melanoma, but this tumor is a great threat to human health. What are the methods of treatment for melanoma, and which method is effective, are of great concern to people who have just been checked for melanoma. Chemotherapy. Chemotherapy, commonly known as “chemotherapy”, refers to the action of chemically synthesized drugs on cancer cells to suppress tumors. Chemotherapy is highly targeted and effective, but the toxic side effects of the drug are also very obvious, and most patients will experience nausea and vomiting and loss of appetite after chemotherapy. Second, radiation therapy. Radiation therapy can be applied to various treatment periods of cancer. Although radiation therapy is effective, while radiation therapy kills cancer cells, some normal tissue cells are also spared to be “shot”, therefore, radiation therapy will have strong toxic side effects on the patient’s body and bring great pain to the patient. Therefore, tumor patients should not be treated with radiation frequently. Surgery. Surgery is one of the preferred methods of clinical treatment for most tumors. However, because of the need to “intervene” inside the patient’s body for resection, old and young patients, weak patients and patients who cannot bear the huge side effects of surgery are not suitable for surgery. Fourth, cell therapy. Cell therapy is also known as CLS autoimmune cell therapy, which mainly uses DC+CIK cells as the leading part. Cellular immunotherapy will have a strong complementary effect when applied together with surgical treatment, chemotherapy and radiotherapy methods. It can have a unique efficacy in restoring and rebuilding the patient’s damaged immune system: preventing tumor recurrence and metastasis when used in conjunction with surgical treatment; prolonging life when used with chemotherapy; and improving the patient’s quality of life.