If you can’t sleep after drinking coffee, you can usually apply the following methods. 1, try not to drink coffee at night before going to bed, if you must drink coffee, try to drink coffee before 13:00 p.m., and try not to drink coffee after 30:00 p.m. 2, you can take a certain amount of vitamin B6 or melatonin vitamin B6 tablets before going to bed, which can play a certain sedative and tranquilizing, but there is no dependence and addictive effect. 3, take a certain amount of estradiol, but must be a small amount and short-term take, for example, estradiol 1mg before bedtime oral, can ease the situation of drinking coffee sleep. 4, drink a certain amount of thick sugar water or thick honey water, using the principle of osmotic diuretic, accelerate the body of coffee and caffeine, so that it is quickly discharged from the urine, can play the exclusion of coffee, to ease the role of sleep effect. The effect of the role of sleep relief.