High bile acids in pregnancy are caused as pregnancy lengthens, and are associated with genetic factors and estrogen levels. If severe, cholestasis of pregnancy may develop, which causes bile to accumulate in the liver and the discharge of bile acids to be blocked, which may raise the concentration of bile acids in the blood, which can irritate the skin and cause itching. If high bile acids are present, they are generally not too harmful to the mother and may endanger the fetus and cause premature or stillbirth. Therefore, if a pregnant woman has cholestasis, she should pay more attention in time, especially to count the number of fetal movements, and it is better to listen to the fetal heartbeat frequently. Normally, cholestasis will return to the normal range at the end of pregnancy and after the child is delivered.