Usually gastrointestinal mesenchymal tumors of 8 centimeters usually require surgery. Surgery is not recommended if it is costly, or if the patient has poor physical fundamentals or distant metastases. Gastrointestinal mesenchymal tumors are mesenchymal tumors originating from the muscular layer of the gastrointestinal tract. The disease has a potential malignant tendency, which can lead to gastrointestinal hemorrhage, vomiting of blood and blood in the stools, abdominal pain, and intestinal obstruction and other symptoms. If the diameter of gastrointestinal mesenchymal tumor reaches 8 centimeters, it needs to be resected under the guidance of doctors. Some patients suffer from hypertension, diabetes mellitus, coagulation disorders and other conditions, such patients to do the operation is more expensive, the condition is not stable generally not recommended resection, so as not to lead to the shortening of the patient’s survival period, the need to control the condition of these diseases and then surgical treatment. In addition, when the patient is older, in poor physical condition, or does not tolerate surgery, the doctor may not recommend removing the gastric mesenchymal tumor, so as to avoid adverse consequences. When gastrointestinal mesenchymal tumors are large in size, patients should pay attention to them and actively cooperate with doctors for appropriate treatment.