A 24-hour urine protein quantification of 1.6 g suggests a nephrocentesis biopsy. Severe elevation of 24-hour urine protein quantification often suggests organic (structural) lesions of the kidneys, because normal people do not have urine protein in a quiet state. If the 24-hour urine protein quantitative amount is below 1g, it may be caused by physiological reasons, at this time there are no obvious symptoms, and it will not cause serious effects, no special treatment is needed, so there is no need to do renal puncture biopsy, and it is enough for regular review. When the 24-hour urine protein quantification is more than 1g, it generally suggests the existence of glomerular injury, and at this time, it is recommended to obtain pathological results through renal puncture biopsy to clarify the diagnosis of the disease, which is decisive for the selection of medication and the prognosis of the disease. 24-hour urine protein quantitative abnormality, it is recommended to regular hospitals, under the guidance of physicians to improve the relevant examination, clear diagnosis, standardized treatment.