Whether surgery is necessary for ascites in advanced stage of ovarian cancer needs to refer to the patient’s condition, some patients have the necessity of surgery, some patients don’t need surgery. When ascites occurs in advanced stage of ovarian cancer, it suggests that the cancer cells have already developed intra-abdominal metastasis. If the patient has more ascites, intra-abdominal chemotherapy and ascites discharge can be carried out to improve the patient’s condition, and after the condition is stabilized, if the patient’s physical condition is still good and surgery is necessary, it is suggested to carry out tumor cytoreduction to slow down the development of the disease, improve the prognosis and prolong the patient’s survival time. If ascites occurs in the advanced stage of ovarian cancer, and the patient has metastasis of vital organs and multiple organ failure, surgery is not meaningful at this time, and it cannot improve the prognosis and increase the pain of the patient, so surgery is not suitable for this kind of patients. It should be noted that the treatment plan of patients should follow the guidance of professional doctors, which can reduce the pain of patients and improve the prognosis.