Those with a systolic blood pressure of 180 mmHg in their blood pressure can be recommended to use 2 tablets of Irbesartan under the supervision of a physician, and the dose of Irbesartan is 75 mg (1 tablet). Irbesartan can be used to treat patients with essential hypertension and hypertension in combination with type 2 diabetes. The generally recommended initial dose of Irbesartan is 150 mg (2 tablets) a day, and Irbesartan’s recommended dose of 150 mg (2 tablets) once daily provides better control of blood pressure over 24 hours than Irbesartan 75 mg (1 tablet) once daily. For patients with a blood pressure of 180 mmHg to seek medical attention, 2 tablets may be recommended under the supervision of a physician. When the blood pressure is 180 mmHg, it is already classified as grade 3 hypertension and usually requires a combination of medications. The common clinical solutions are combined with lorazepam-type antihypertensive drugs, such as metoprolol tartrate tablets, bisoprolol fumarate, carvedilol tablets; combined with diphenhydramine-type antihypertensive drugs: such as amlodipine benzenesulfonate tablets, nifedipine controlled-release tablets, etc.; and may also be used in conjunction with hydrochlorothiazide and indapamide. There are differences according to the patient’s situation. Adverse effects of Irbesartan include edema, flushing, dizziness, tachycardia, cough, diarrhea, nausea, vomiting, dyspepsia, fatigue, and chest pain. Contraindications are allergy to the components of the product, pregnant women, people with moderate to severe renal impairment. The specific use of medication should follow the doctor’s instructions.