Postmenopausal endometrial thickening of 16mm with a bit of running water and blood flow signals is dangerous, it is recommended to go to the hospital as soon as possible to receive a systematic examination. Postmenopausal endometrial more than 5mm suggests that there may be a problem, the patient is currently endometrial thickening 16mm with water and blood flow signal, this situation should be timely to go to the hospital for a full range of systematic examination and scraping, the uterine cavity inside the uterus and cervical canal of the uterine endometrium were scraped part of the tissue, and sent to the pathology of the test. The scraped tissues are tested for pathology to rule out the possibility of cancer. If it is cancer, it is recommended to communicate with the doctor about the treatment plan. Common treatment options include removal of the uterus and its adnexa with adjuvant treatments such as radiotherapy. If cancer is ruled out, endometrial polyps are usually considered. Damage or inflammation of the endometrium may lead to endometrial polyps, and it is recommended to identify the cause and remove them in time to avoid malignant changes. Postmenopausal women should also undergo regular annual screening for breast cancer and cervical cancer for early intervention and treatment, and seek immediate medical attention if discomfort occurs.