Cold and flu throat is always itchy, cough may be related to viral infection. Most colds are due to acute inflammation of the nasal cavity, pharynx, throat and other parts of the respiratory syncytial virus, echovirus, coxsackievirus, rhinovirus, etc., and are often manifested in the clinic as sneezing, runny nose, nasal congestion, itchy throat, cough and other symptoms. Cold itchy throat, cough and other symptoms may be related to the virus-induced inflammatory mediators caused by the upper respiratory tract afferent nerve hypersensitivity state, but also may be related to the virus-induced pharyngeal mucosal congestion and edema. It is important to note that symptoms such as itchy throat and cough can also be caused by other diseases, such as pharyngitis and gastroesophageal reflux disease. If the symptoms do not improve or aggravate, it is recommended to go to a regular hospital for consultation, improve the examination, clarify the diagnosis, and actively cooperate with the doctor’s treatment.