Pancreatic cancer is a digestive tumor with very high malignancy. Many patients with pancreatic cancer will show obvious symptoms of fatigue and weakness, severe abdominal pain, jaundice, anemia, emaciation, ascites, and even cachexia before they die. Some patients may also die due to complications, such as gastrointestinal hemorrhage caused by pancreatic cancer. Patients may have a lot of vomiting blood and black stool within a short period of time, which eventually causes hemorrhagic shock, manifested as pale face, wet and cold extremities, fine and rapid pulse, and finally leads to coma and death. If combined with acute septic obstructive cholangitis, there will also be obvious high fever and chills. In addition to the symptoms of shock, there may also be symptoms of suppression of the central nervous system, such as drowsiness and coma. For patients with end-stage pancreatic cancer, the main focus is on symptomatic supportive treatment to improve the quality of life so that patients can receive better end-of-life care.