Pimples around the lips may be caused by stomach fire or heart fire, and the specific pattern should be judged in conjunction with the patient’s tongue and pulse, as well as other signs and symptoms. According to the meridian circulation, the branches of the Heart meridian start from the heart, go up the esophagus and finally reach the eyes. When the heart is on fire, the heat traveling up the meridian may lead to blistering and acne on the lips and mouth, sores on the tongue and mouth, and may be accompanied by swollen and painful gums, bleeding, dry mouth and throat, and insomnia and excessive dreaming. According to the basic theory of Chinese medicine, the mouth is the door of the stomach, the stomach fire (stomach fire and heat evil exuberance) up inflammation of the mouth and lips leading to acne, gastric hyperfunction and the emergence of heat such as heartburn, dry mouth and thirst, vomiting and so on. Patients with severe acne can go to the Chinese medicine department to determine the type of disease and treatment medication after diagnosis. Usually pay attention to the diet, regular life and facial cleanliness and hygiene.