Lactasexan can be taken together with Bifidobacterium bifidum, but both are probiotic preparations, and clinical advice is to use a single drug, the specific use should be under the guidance of a doctor. Current drug studies do not suggest that the combined use of Lactasexan and Bifidobacterium bifidum will interfere with each other’s therapeutic effects, so only from the perspective of the drug’s principle of action, the two can be taken at the same time. However, it should be noted that since both Lactasexant and Bifidobacterium belong to the group of intestinal probiotics, it is often recommended that a single dose of the drug be administered first in clinical practice, especially for first-time treatments, so as to facilitate observation of the drug’s specific efficacy in the patient, and then to consider switching to a different drug or adding a new one if the effect of the drug is not satisfactory. In addition, it should be noted that the contraindications and adverse effects of lactase inhibitor and bifidobacteria are not clear, so those who have the need to use these two drugs must be strictly under the guidance of a doctor to use the drug, and closely observe the reaction after the use of the drug, if there is any maladaptation, timely consult a doctor for disposal. Do not blindly use the drug or increase or decrease the dosage by yourself, so as not to cause adverse consequences.