Atorvastatin calcium can be taken with aspirin under the guidance of a physician. 1. Atorvastatin calcium is mainly used to reduce the level of blood lipids in the clinic, especially used to reduce the level of low-density lipoprotein cholesterol, can effectively prevent and treat the occurrence of atherosclerosis; the main clinical side effects manifested in liver damage, muscle adverse reactions, etc., allergic to this drug, liver aminotransferase level more than three times the normal high value can not be taken. 2. Aspirin is an inhibitor of platelet aggregation, used to prevent transient ischemic attack, atrial fibrillation, artificial heart valve surgery, myocardial infarction and other thrombosis; clinical attention to patients allergic to this drug, patients with gastrointestinal history of serious bleeding can not be taken; the most common side effects manifested as bleeding. Atorvastatin calcium and aspirin are often used jointly in clinical practice, atorvastatin calcium stabilizes plaque to avoid plaque rupture, aspirin prevents thrombosis, can be used for coronary atherosclerotic heart disease, stable angina pectoris, old myocardial infarction, cerebral thrombosis, ischemic cardiomyopathy treatment. Clinical need for oral aspirin with atorvastatin calcium, it is recommended to consult a regular hospital cardiologist, not blindly use their own medication.