Clinically, insulin is divided into ultra-short-acting insulin, short-acting insulin, intermediate-acting insulin, long-acting human insulin analogues and premixed insulin according to the different onset and duration of action of the drug. 1.Quick-acting human insulin analogues: the onset of action is 15 minutes, the peak effect is 30-45 minutes, and the duration is about 2-4 hours, such as Novalis and Unilog. 2.Short-acting insulin: It is the most commonly used kind of common insulin, which is a colorless and transparent liquid with an onset time of 20-30 minutes, a peak effect of 2-4 hours, and a duration of 6-8 hours after subcutaneous injection, such as Novolin R and Eugenol R. 3, medium-acting insulin: also known as “low protein zinc insulin”. Milky white turbid liquid, the onset of action is 1.5 to 4 hours, the peak effect is 4 to 12 hours, and the duration is about 14 to 20 hours. Such as Novolin N and Eugenol N, etc. 4, long-acting human insulin analogues: the main ones are “glargine insulin” and “detergent insulin”, which are characterized by stable drug absorption after subcutaneous injection, stable plasma concentration and no obvious blood peak, and the hypoglycemic effect can be maintained once a day by subcutaneous injection. The hypoglycemic effect can be maintained for 24 hours with one daily subcutaneous injection, which can better simulate the secretion of normal basal insulin. 5, premixed insulin: short-acting insulin (R) and medium-acting insulin (N) are mixed in a certain ratio in advance, called premixed insulin. For example, Novolin 30R, Novolin 50R, Utrolin 70/30. 30R means that 30% of short-acting R is mixed with 70% of medium-acting N insulin; 50R means that short-acting R and medium-acting N each account for 50%. All of the above drugs have an onset time of 30 minutes, a peak time of 2 to 8 hours and a duration of 12 to 24 hours.