Chest pain in the middle of the upper side may be related to trauma, angina, pleurisy, etc., different causes of different medications, commonly used drugs are Panax ginseng tablets, nifedipine controlled release tablets, cefadroxil capsules, etc., it is recommended to use the medication under the guidance of a doctor. 1. Trauma: such as rib fracture, muscle strain and other trauma may cause pain in the middle of the upper side of the chest, generally can follow the doctor’s instructions to use Panax ginseng tablets, bruxism pills and other drugs to ease the treatment. 2. Angina pectoris: when this kind of patients by coronary artery stenosis or spasm caused by myocardial ischemia, hypoxia can be manifested as the symptoms of pain in the middle of the upper side of the chest, generally can be prescribed the use of nifedipine controlled-release tablets, nitroglycerin injections and other drugs treatment. 3. Pleurisy: chest pain in the middle of the upper side may be one of the symptoms of pleurisy, such patients should follow the doctor’s instructions on the cause of treatment. For example, for pleurisy caused by bacterial infection, antibiotics such as cefadroxil capsules and norfloxacin tablets can be used as prescribed by doctors, and for tuberculosis pleurisy, anti-tuberculosis treatment such as isoniazid tablets and pyrazinamide tablets can be used as prescribed by doctors. The presence of the above factors, should promptly consult a doctor, under the guidance of the doctor to use medication.