The hands are the most parts of our contact with external objects, and are extremely vulnerable to injury. Some small wounds do not look so serious, but I do not know that after the injury a special bacteria is quietly attacking …… First acquaintance with tetanus Tetanus is caused by Clostridium tetani immersed in the body through skin or mucosal wounds, growing and multiplying in an oxygen-deprived environment, producing toxins and It is a specific infection that causes paroxysmal muscle spasms. According to the clinical manifestations, there are 3 phases: incubation period, prodromal phase and attack phase. 1. The incubation period is usually 7-8 days, with a minimum of 24 hours and a maximum of several months. The shorter the incubation period, the worse the prognosis. If the onset of the disease is slow, there may be generalized weakness, dizziness, headache, weakness in chewing, local muscle tightness, tearing pain, hyperreflexia and other symptoms before the onset of the disease. 2. The prodromal phase is characterized by weakness, dizziness, headache, weakness in chewing, inconvenience in opening the mouth, irritability, yawning, local muscle tightness, pain, and hyperreflexia. The main feature of the disease is the difficulty in opening the mouth. The duration of the disease is usually 3 to 4 weeks. If the disease is treated actively and no special complications occur, the degree of the attack can be gradually reduced and the remission period is about 1 week on average. However, muscle tension and hyperreflexia can continue for a period of time; some psychiatric symptoms such as hallucinations, speech and confusion of action can also appear during the recovery period, but they can mostly recover on their own. 3, the typical symptoms of the seizure period are paroxysmal strong spasms on the basis of muscle tension contraction. Severe patients even need tracheotomy and intubation to maintain a clear airway. Prevention is better than cure. Proper wound management and artificial immunization can effectively prevent tetanus. Wounds, internal foreign bodies, necrotic tissue, and accumulated blood should be thoroughly removed when encountering suspicious wounds. Rinse and wet dress the wound with 3% hydrogen peroxide solution to destroy the anoxic environment conducive to bacterial growth. If peroxide is not available, promptly flush with plenty of soapy water. Administer tetanus antitoxin (TAT) 1500-3000 U or human tetanus immunoglobulin subcutaneously as early as possible to casualties who did not receive active immunization before the injury. Avoid skin injuries. The following cases should be seen in hospital for tetanus antitoxin injection: 1. Any deep and narrow traumatic incision, such as a wooden thorn or rusty nail puncture wound; 2. Wounds that are shallow but stained with human and animal feces; 3. Emergency delivery or abortion outside the hospital without sterile treatment; 4. Before the removal of old foreign bodies.