Glomerular filtration rate labs determine its clinical significance through its reference value to see if there is any abnormality, which is judged by professional clinicians. Glomerular filtration rate refers to the amount of plasma fluid filtered out by the glomerulus per unit of time (minute), under normal circumstances, the glomerular filtration rate is usually between 80~120ml/min. The laboratory reference value varies slightly according to different hospitals, and the hospital reference value shall prevail. Decreased glomerular filtration rate can be seen in acute renal insufficiency such as diarrhea, obstruction and other factors, after correcting the reversible factors, most of the renal function can be restored to normal; can also be seen in chronic renal insufficiency, such as chronic nephritis, diabetic nephropathy, hypertensive renal damage and so on. Elevated glomerular filtration rate can be seen in physiological factors such as high protein diet, pregnancy, etc., but also in pathological factors such as early diabetic nephropathy. If the glomerular filtration rate is abnormal, it is recommended that the patient should go to the regular hospital in time for treatment under the guidance of the doctor.