Acute glomerulonephritis and acute pyelonephritis are two completely different concepts. First, the etiology is different: acute glomerulonephritis is often caused by beta-streptococcal infection, while acute pyelonephritis is often caused by Escherichia coli; second, the clinical manifestations are different. Acute glomerulonephritis often presents suddenly with hematuria, proteinuria, edema and hypertension, and may be accompanied by transient renal insufficiency, while acute pyelonephritis belongs to patients with upper urinary tract infection, often Patients with acute pyelonephritis often have a tendency to heal themselves, and there is no special treatment, often rest and symptomatic treatment, which mainly includes diuretic and anti-swelling treatment and antihypertensive treatment. The commonly used antibiotics include semi-synthetic penicillins, cephalosporins and quinolones.