If the systemic symptoms of acute pyelonephritis are not obvious, cefixime is 1 tablet/time, 3 times/day, if the systemic symptoms are obvious, 2 tablets/time, 3 times/day can be used, and the urine routine and bacterial examination should be tested regularly. In case of chronic pyelonephritis, the program should be formulated according to the condition and the results of drug sensitivity test. According to the examination results to adjust the use of drugs.