Liver transaminase 1000+ can usually be cured if it is not caused by chronic liver diseases such as viral hepatitis, cirrhosis, etc. The exact effect varies from person to person. Transaminase refers to alanine aminotransferase, the normal value is usually not more than 40, if the transaminase more than 1000, it means that the liver cells are obviously damaged, and even the liver cells may be necrotic. The more common causes of elevated transaminases in clinical practice include viral hepatitis, alcoholic liver disease, and drug-induced liver injury. If there is no chronic hepatitis, the aminotransferases can be gradually normalized after timely medical treatment. If the transaminase 1000 is caused by chronic hepatitis B, the treatment can only relieve the symptoms and improve the prognosis, but often can not completely cure the disease. It is recommended that patients with transaminases of more than 1000 should seek medical treatment in time to find the primary cause and take professional measures to treat the disease.