The pain of big toe protrusion is considered to be the symptoms of bunion, which needs to be treated with general treatment, medication and surgery under the guidance of the doctor. 1. General treatment: Choose the right shoes, avoid squeezing the big toe as much as possible; wear corrective tools such as silicone toe pads to relieve pain and prevent the development of deformity. 2. Medication: Non-steroidal anti-inflammatory drugs such as Celecoxib can be prescribed to help control inflammation and relieve pain. 3. Surgical treatment: For those with severe deformity and pain, and for whom non-surgical treatment is ineffective, soft-tissue surgery, osteotomy and orthopedic surgery can be performed. It is recommended to go to the regular hospital in time, under the guidance of the doctor for standardized treatment.