Positive hepatitis B two-to-one half 2.5 refers to positive surface antibody and hepatitis B core antibody among the five indicators of hepatitis B, which usually do not need special treatment. Hepatitis B surface antibody is a protective antibody, which can effectively prevent hepatitis B virus infection, and its positivity indicates that the human body has certain immunity against hepatitis B virus; hepatitis B core antibody positivity indicates that the patient has current infection of hepatitis B virus or has been infected with hepatitis B virus in the past. Therefore, when both hepatitis B surface antibody and hepatitis B core antibody are positive, it means that the patient’s previous infection with hepatitis B virus has been cured, and the patient has the corresponding immunity to hepatitis B virus, so no special treatment is usually needed. Chronic hepatitis B is very harmful, may lead to cirrhosis, liver cancer and other serious consequences, so patients should be treated in time to prevent further deterioration of the disease.