A small bump on the epididymis then possible causes: 1. Epididymitis, when inflammatory changes can occur local enlargement, the acute phase can be accompanied by local swelling, painful sensation. In chronic cases, the incision is not felt, and it is a local inflammatory and scarring nodule with a hard texture, sometimes closely adhered to the testicle, so it is not easy to distinguish from testicular nodules. 2. Tuberculosis of the epididymis, which can appear as a small bump on the epididymis with a hard texture, accompanied by fever or night sweats, mostly secondary to tuberculosis, and the patient may have a cough or coughing sputum. Symptoms. Tuberculin test, ultrasound and chest x-ray are needed to confirm the diagnosis. When tuberculous lesions appear in the epididymis, except for small bumps in the epididymis, they may also be accompanied by sclerosis of the vas deferens, with string-like or Buddha bead-like changes in the vas deferens and a hard texture. Severe patients may have obstructive azoospermia or infertility due to sperm transport disorder.