Insomnia is a multi-factor sleep disorder, from the short-term effects, insomnia caused by lack of sleep will make people depressed, fatigue, concentration, directly affecting the next day’s work and study. The long-term sleep deprivation may induce various physical diseases, physiological discomfort will further affect the sleep, into a vicious circle, its serious effects are mainly the following aspects: 1, mental disorders: the brain does not get sufficient rest, easy ischemia and hypoxia, brain cell metabolism disorders, accelerating brain cell death, so that people in a trance, slow reaction, memory loss, affect the brain’s creative thinking, or manifest Anxiety, depression, symptoms related to plant nerve dysfunction; 2, endocrine disorders: long-term insomnia disrupts the human biological clock, the body’s hormone levels are out of balance, accelerating human aging, resulting in skin pigmentation, excessive sebum secretion, wrinkles, enlarged pores, severe hair loss and sexual dysfunction and other adverse effects, can also cause early menopause in women, reduced ovarian function, etc.; 3, stunted development. Growth hormone is a peptide hormone secreted by the pituitary gland, which can promote the growth of bones, internal organs and other tissues and organs, and promote protein synthesis. The secretion level of growth hormone is related to sleep, such as long-term insomnia in adolescents, which may lead to poor physical development, mental retardation, etc.; 4, impaired immune function: lack of sleep can lead to a decrease in the body’s immunity, reducing the body’s ability to resist pathogenic microorganisms such as bacteria and viruses, and 5, induce physical diseases: long-term insomnia may induce a variety of diseases or aggravate the original disease, such as cardiovascular disease, hypertension, diabetes, digestive system diseases, etc., the most obvious harm to the elderly, making the elderly vulnerable to neurasthenia, dementia, especially coronary heart disease, arrhythmia of elderly patients, insomnia at night can even lead to sudden death.