Liver palms can be seen in some healthy people or people with chronic liver diseases such as cirrhosis and liver cancer, and their increasing visibility is related to the degree of capillary expansion. Liver palms, i.e. flaky congested or pink spots on the palms of the hands at the intersection of the big and small fishes, will appear in normal people, such as the increase of estrogen in the body of pregnant women, the capillaries will expand gradually, and liver palms will appear or become obvious gradually. Chronic liver disease such as cirrhosis or liver cancer, liver function is reduced, can affect the patient’s endocrine, in the metabolic process of sex hormones, the liver to estrogen inactivation is reduced, resulting in increased estrogen, there is capillary dilation, congestion, caused by the liver palms obvious, serious cases can be spider nevus appearance. Liver palms are getting heavier and heavier, which indicates that the degree of blood vessel dilation and congestion is deep, and is generally not closely related to the severity of the disease. Patients with symptoms of liver palms are advised to consult a doctor to clarify the cause of the disease and then target treatment.