How to remove small particles on the face, first need to consider what kind of skin disease such small particles belong to. 1, if the small particles are just ordinary whiteheads acne, or papular acne, generally according to the acne treatment plan can be treated, you can apply topical adapalene gel or clindamycin gel and so on. Then take oral salvianolone capsules, 3 times a day, 4 pills a time. 2. If such small particles do not belong to the type of acne, but to eczema, anti-allergy treatment is needed, usually topical tacrolimus cream, or Eudragel cream, and then oral medication, you can take oral loratadine, etc.