Subcutaneous gangrene occurs in pressurized parts of the body, most commonly in the back and buttocks, but also in the occiput, sacrum, legs and other parts of the body. Symptoms include local symptoms and systemic symptoms, such as local pain and fever. 1. Local symptoms: the local skin temperature of the pressure area is elevated, red and swollen, and there is pain on palpation; the local hardness can be seen, and the boundary with the surrounding tissues is not clear; the lesion progresses rapidly, and the foci can develop and expand rapidly within a few hours, and the skin of the lesion area is dark red at this time, and the texture becomes soft, and there may be a fluctuating sensation when pressed. If it fails to cut and drain in time, it can lead to necrosis of subcutaneous tissue, the contents turn into bloody liquid, the central part of the skin turns black, and the skin breaks down and pus flows. 2. Systemic symptoms: including convulsions, high fever, etc., body temperature up to 40 ℃. In addition, there are cyanosis, drowsiness, delirium, coma, abdominal distension, dyspnea, skin bruises and petechiae. Some of the serious condition of the body temperature does not rise, manifested as toxic shock, and even life-threatening. If long-term bedridden patients or newborns appear uncomfortable, a comprehensive examination should be done. If localized redness and swelling of the skin with unclear boundaries are found, immediate medical attention and timely treatment measures are recommended.