Gallbladder wall roughness, gallbladder polypoid lesions, can be given surgical treatment and conservative treatment options, drugs should be applied under the guidance of the doctor. 1. Hirsutism of gallbladder wall: It is considered to be caused by cholecystitis, and it can also be considered to be caused by congestion and edema of gallbladder wall due to friction between gallbladder stones and gallbladder wall, which is mainly manifested as right epigastric pain, abdominal distension, and vomiting, etc. In mild cases, conservative treatment can be given. Mild cases can be given conservative treatment, giving antibiotics (such as cefoperazone, cefuroxime, etc.) anti-infection, antispasmodic and analgesic (such as scopolamine, etc.) drugs. If symptoms recur, give laparoscopic cholecystectomy. 2. Gallbladder polyps: asymptomatic gallbladder polyps, polyp size is less than one centimeter, and follow-up observation, did not see enlargement or increase, can be treated conservatively. If it is a single gallbladder polyp, and the gallbladder polyp is large and has a tendency to grow, laparoscopic cholecystectomy will be given. If there is any related disease, it is recommended to go to the hospital for treatment as soon as possible to avoid delay.