A positive hepatitis B core antibody does not usually develop into a hepatitis B patient. Hepatitis B core antibody positivity means that you have been infected with Hepatitis B in the past, but your body has cleared the virus through your own immunity. In this case, the person is normal and will not develop hepatitis B and does not need treatment. Very few hepatitis B infected people have mutated the hepatitis B virus in their bodies, the surface antigen of hepatitis B has changed from positive to negative, and they only show positive hepatitis B core antibody, but their hepatitis B viral load is positive, which is also a case that needs to be treated. Hepatitis B core antibody-positive people may activate the hepatitis B virus when using monoclonal antibodies or undergoing hematopoietic stem cell transplantation, and need to be treated with prophylactic hepatitis B antiviral drugs under the guidance of a specialist.