Glutamate dehydrogenase refers to the enzyme glutamate dehydrogenase, and its elevation has been linked to diet, medications, hepatitis, and cirrhosis. 1. Diet: Eating too greasy food, such as barbecue, fried food, hot pot, etc., or drinking a lot of alcohol before the examination may lead to high glutamate dehydrogenase value. Patients can return to normal after dietary adjustments and regular work and rest. 2. Drugs: Taking anti-tuberculosis drugs such as rifampicin, isoniazid, ethambutol, antipyretic drugs such as hydroxybutazone, aminopyrine, anti-inflammatory pain relievers, and antibiotics such as benzylpenicillin, gentamicin, etc. can also cause high glutamate dehydrogenase. The value usually decreases about 2 weeks after stopping the medication. 3. Hepatitis, cirrhosis: acute hepatitis, cirrhosis of the liver can also cause glutamate dehydrogenase elevation, the patient may appear fatigue, nausea and vomiting, right upper abdominal pain and other symptoms, need to be combined with other tests to clarify the diagnosis. Mild elevation can be improved by adjusting diet and lifestyle habits, while those with significant elevation should consult the doctor for drug treatment. Of course, high glutamate dehydrogenase can also be caused by other reasons, if the value is significantly increased, you should go to the hospital in time to find out the cause.