Itchy erythema in the groin, if it is caused by eczema, you can use glyburide lotion, glucocorticoid cream or gel, etc.; if it is caused by urticaria, you can use fexofenadine, loratadine and other drugs for treatment. 1. Eczema: itchy erythema in the groin may be caused by eczema, on the basis of erythema, there may be pinhead to grain size papules, papules, and small blisters may appear in severe cases. Can be used externally glycerine lotion, glucocorticoid cream or gel, oozing more than 3% boric acid solution can be used to cold wet compresses, there are vesicles, but not much exudate can be used when zinc oxide oil. 2. Urticaria: inguinal erythema itch, if the erythema is lumpy and elevated, and accompanied by angioedema, considered to be caused by urticaria, generally can use fexofenadine, loratadine, diclofenac sodium and other antihistamine drugs for treatment. Itchy erythema in the groin may also be caused by other reasons, it is recommended that patients seek medical attention in a timely manner, improve the examination to clarify the cause of the disease, standardized treatment in accordance with the doctor’s instructions, the use of drugs need to follow the doctor’s instructions.