You can get a breathalyzer test with cold medicine. A breath test, generally referred to as a C13 or C14 test, is a way to check the body for H. pylori infection. When the test is positive, it suggests the presence of H. pylori infection in the stomach; negative results suggest the absence of H. pylori infection. H. pylori infection mainly requires treatment with acid-suppressing drugs and antibiotics. Cold medicines are not antibiotics and generally do not affect the growth and reproduction of H. pylori in the stomach, while antibiotics such as amoxicillin, clarithromycin, metronidazole, etc. have the effect of inhibiting the growth of H. pylori, and when such antibiotics are taken they affect the results of the breath test, and it is generally necessary to stop taking the medicine for two weeks before the breath test is performed, whereas taking cold medicines does not affect the results of the breath test. In addition, the breath test may also refer to the measurement of exhaled nitric oxide, which is mostly used in the diagnosis of bronchial asthma, and this time taking cold medicine will not affect the measurement. If you need to do the breath test examination, please consult the hospital in time, under the guidance of the physician.