Stomach distension, aggravated when lying down may be due to diet, indigestion, chronic gastritis and other factors, which can be relieved by general treatment, medication and surgery. 1. General treatment: patients can promote gastrointestinal peristalsis to facilitate the expulsion of gas and improve gastric distension through gentle clockwise massage, hot compresses or walking, jogging and other exercises in the abdomen. Usually should pay attention to improve the dietary habits and structure, avoid overeating, avoid eating beans, sweet potatoes and other easy to produce gas food, try to eat small meals, chewing and swallowing slowly. 2. Taking drugs: If the patient is caused by peptic ulcer, chronic gastritis and other diseases, he can take omeprazole, bismuth potassium citrate and other drugs to inhibit the secretion of gastric acid and protect the gastric mucosa. When accompanied by Helicobacter pylori infection, eradication treatment can be carried out by the quadruple method, i.e. one proton pump inhibitor such as omeprazole + one bismuth agent such as colophony bismuth + two antibiotics such as amoxicillin and clarithromycin. If it is caused by dyspepsia, you can take digestive enzyme preparations such as compound digestive enzymes to promote the digestion of food; if the patient is accompanied by gastric insufficiency, you can take domperidone and other prokinetic drugs to promote gastrointestinal peristalsis and accelerate the emptying of food. 3. Surgery: Intestinal obstruction, gastric cancer and other diseases can also lead to gastric distension, and surgery can be considered. If the patient has long-term or recurrent gastric distension, which is aggravated when lying down, it is recommended to consult a doctor in time, and the medication should be taken strictly according to the doctor’s prescription, and should not be used by oneself, so as to avoid delaying or even aggravating the condition.