Mild mitral or tricuspid regurgitation may be asymptomatic. In severe mitral regurgitation, symptoms such as dyspnea and fatigue may occur; in severe tricuspid regurgitation, symptoms of right heart failure such as ascites and hepatomegaly may occur. The mild mitral regurgitation is normal physiological condition, patients can be lifelong without symptoms, but for the more serious degree of regurgitation, due to the reduction of cardiac output, which will be manifested as reduced work endurance, fatigue and other symptoms, but also manifested in varying degrees of dyspnea, the development of the disease to the advanced stage can also be seen in appetite loss, abdominal distension and other symptoms of the right heart failure. Tricuspid regurgitation can be asymptomatic in mild cases. With the further development of the disease, the regurgitated blood can be stagnated in the right atrium, leading to right heart insufficiency, which can show symptoms of blood stasis in the body circulation, such as jugular vein varicose, ascites, hepatomegaly, and double lower extremity edema. If the above symptoms of mitral regurgitation occur, it is recommended to go to the hospital as soon as possible to avoid further development of the condition with serious complications or even death.