The exact length of time a person can live without a large intestine is determined by the extent of the large intestine lesion removed and the severity of the patient’s condition. For some benign lesions, such as congenital megacolon, there is no effect on human life expectancy after removal of the large intestine for this disease, and as long as regular post-operative review and regular diet, long-term survival is possible. For some malignant lesions, such as colon cancer and rectal cancer, such patients need to remove the large intestine in addition to the surrounding lymph nodes, and if the stage of the tumor is early and the surgery is timely, the five-year survival rate can reach more than 70%. Therefore, in order to prolong life after colon resection, early detection, early diagnosis and early treatment should be achieved, and these means can ensure that life is not threatened under normal circumstances.